FZD4 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-66429
Additional Names:: CD344,EVR1,FEVR,FZD4,FZD4S,Fz-4,Fz4,FzE4,GPCR,hFz4
Application:: IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human FZD4 (NP_036325.2).
Uniprot:: Q9ULV1
Synonyms:: CD344;EVR1;FEVR;frizzled 4, seven transmembrane spanning receptor;frizzled family receptor 4;frizzled homolog 4;frizzled-4;Fz-4;Fz4;FZD4S;FzE4;GPCR;hFz4;WNT receptor frizzled-4
Extra Details:: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.