E-AB-66290
MZB1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66290
- Additional Names:
- MEDA-7,MZB1,PACAP,pERp1
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MZB1 (NP_057543.2).
- Uniprot:
- Q8WU39
- Synonyms:
- caspase-2 binding protein;HSPC190;marginal zone B- and B1-cell-specific protein;MEDA-7;mesenteric estrogen-dependent adipose 7;mesenteric oestrogen-dependent adipose gene- 7;PACAP;pERp1;plasma cell-induced ER protein 1;plasma cell-induced resident endoplasmic reticulum protein;plasma cell-induced resident ER protein;proapoptotic caspase adapter protein;proapoptotic caspase adaptor protein
- Extra Details:
- Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
- Shipping Conditions:
- Blue Ice