E-AB-66179
CYP1B1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66179
- Additional Names:
- ASGD6,CP1B,CYP1B1,CYPIB1,GLC3A,P4501B1
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CYP1B1 (NP_000095.2).
- Uniprot:
- Q16678
- Synonyms:
- aryl hydrocarbon hydroxylase;ASGD6;CP1B;CYPIB1;cytochrome P450 1B1;cytochrome P450, family 1, subfamily B, polypeptide 1;cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile);dioxin-inducible cytochrome p450;flavoprotein-linked monooxygenase;GLC3A;hydroperoxy icosatetraenoate dehydratase;microsomal monooxygenase;P4501B1;xenobiotic monooxygenase
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
- Shipping Conditions:
- Blue Ice