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E-AB-66019

PER2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-66019
Additional Names:
FASPS,FASPS1,PER2
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human PER2 (NP_073728.1).
Uniprot:
O15055
Synonyms:
circadian clock protein PERIOD 2;FASPS;FASPS1;hPER2;period 2;period circadian clock 2;period circadian protein 2;period circadian protein homolog 2;period homolog 2
Extra Details:
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.
Shipping Conditions:
Blue Ice