E-AB-66005
A1CF Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66005
- Additional Names:
- A1CF,ACF,ACF64,ACF65,APOBEC1CF,ASP
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human A1CF (NP_055391.2).
- Uniprot:
- Q9NQ94
- Synonyms:
- ACF;ACF64;ACF65;apo-B RNA editing protein;apobec-1 complementation factor (ACF) (ASP);APOBEC-1 stimulating protein;APOBEC1 complementation factor;APOBEC1-stimulating protein;APOBEC1CF;ASP
- Extra Details:
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice