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E-AB-65959

TH Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65959
Additional Names:
DYT14,DYT5b,TH,TYH
Application:
IHC, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TH (NP_000351.2).
Uniprot:
P07101
Synonyms:
dystonia 14;DYT14;DYT5b;TYH;tyrosine 3-hydroxylase;tyrosine 3-monooxygenase
Extra Details:
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Shipping Conditions:
Blue Ice