E-AB-65956
SLC25A19 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65956
- Additional Names:
- DNC,MCPHA,MUP1,SLC25A19,THMD3,THMD4,TPC
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human SLC25A19 (NP_068380.3).
- Uniprot:
- Q9HC21
- Synonyms:
- DNC;MCPHA;mitochondrial thiamine pyrophosphate carrier;mitochondrial uncoupling protein 1;MUP1;solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19;solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19;Solute carrier family 25 member 19;THMD3;THMD4;TPC
- Extra Details:
- This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
- Shipping Conditions:
- Blue Ice