E-AB-65896
Syndecan-1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65896
- Additional Names:
- CD138,SDC,SDC1,SYND1,syndecan
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human Syndecan-1 (NP_002988.3).
- Uniprot:
- P18827
- Synonyms:
- CD138;CD138 antigen;heparan sulfate proteoglycan fibroblast growth factor receptor;SDC;SYND1;syndecan;syndecan proteoglycan 1;syndecan-1
- Extra Details:
- The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
- Shipping Conditions:
- Blue Ice