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E-AB-65867

TPM3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65867
Additional Names:
CAPM1,CFTD,HEL-189,HEL-S-82p,NEM1,OK/SW-cl.5,TM-5,TM3,TM30,TM30nm,TM5,TPM3,TPMsk3,TRK,hscp30
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TPM3 (NP_689476.2).
Uniprot:
P06753
Synonyms:
alpha-tropomyosin, slow skeletal;CAPM1;CFTD;cytoskeletal tropomyosin TM30;epididymis luminal protein 189;epididymis secretory sperm binding protein Li 82p;Gamma-tropomyosin;heat-stable cytoskeletal protein 30 kDa;HEL-189;HEL-S-82p;hscp30;NEM1;OK/SW-cl.5;TM-5;TM3;TM30;TM30nm;TM5;TPM3nu;TPMsk3;TRK;tropomyosin 3 nu;tropomyosin alpha-3 chain;tropomyosin gamma;Tropomyosin-3;tropomyosin-5
Extra Details:
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice