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E-AB-65812

APOA1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65812
Additional Names:
APOA1,apo(a)
Application:
IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human APOA1 (NP_000030.1).
Uniprot:
P02647
Synonyms:
apo-AI;apo(a);apolipoprotein A-I;Apolipoprotein A1;epididymis secretory sperm binding protein;HPALP2
Extra Details:
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
Shipping Conditions:
Blue Ice