PRMT1 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-65778
Additional Names:: ANM1,HCP1,HRMT1L2,IR1B4,PRMT1
Application:: IHC
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PRMT1 (NP_938074.2).
Uniprot:: Q99873
Synonyms:: ANM1;HCP1;heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2;histone-arginine N-methyltransferase PRMT1;HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2;HRMT1L2;interferon receptor 1-bound protein 4;IR1B4;protein arginine N-methyltransferase 1
Extra Details:: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.