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E-AB-65772

AKR1C2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65772
Additional Names:
AKR1C-pseudo,AKR1C2,BABP,DD,DD-2,DD/BABP,DD2,DDH2,HAKRD,HBAB,MCDR2,SRXY8,TDD
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human AKR1C2 (NP_995317.1).
Uniprot:
P52895
Synonyms:
3-alpha-HSD3;AKR1C-pseudo;aldo-keto reductase family 1 member C2;BABP;chlordecone reductase homolog HAKRD;DD;DD-2;DD/BABP;DD2;DDH2;Dihydrodiol dehydrogenase 2;dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III;Dihydrodiol dehydrogenase/bile acid-binding protein;HAKRD;HBAB;MCDR2;pseudo-chlordecone reductase;SRXY8;TDD;testicular 17,20-desmolase deficiency;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;type II dihydrodiol dehydrogenase;Type III 3-alpha-hydroxysteroid dehydrogenase
Extra Details:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice