E-AB-65756
DCPS Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65756
- Additional Names:
- ARS,DCPS,DCS1,HINT-5,HINT5,HSL1,HSPC015
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human DCPS (NP_054745.1).
- Uniprot:
- Q96C86
- Synonyms:
- 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase;ARS;DCS-1;DCS1;decapping scavenger enzyme;epididymis secretory sperm binding protein;heat shock-like protein 1;HINT-5;hint-related 7meGMP-directed hydrolase;HINT5;histidine triad nucleotide-binding protein 5;histidine triad protein member 5;homolog of C. elegans 7meGMP-directed hydrolase dcs-1;HSL1;HSPC015;m7GpppX diphosphatase;mRNA decapping enzyme;scavenger mRNA-decapping enzyme DcpS
- Extra Details:
- This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′, mRNA cap structure, which appear in the 3′, →, 5′, mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
- Shipping Conditions:
- Blue Ice