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E-AB-65742

CA12 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65742
Additional Names:
CA-XII,CA12,CAXII,HsT18816,T18816
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human CA12 (NP_001209.1).
Uniprot:
O43570
Synonyms:
CA-XII;carbonate dehydratase XII;carbonic anhydrase 12;carbonic anhydrase XII;carbonic dehydratase;CAXII;HsT18816;T18816;tumor antigen HOM-RCC-3.1.3
Extra Details:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene.
Shipping Conditions:
Blue Ice