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E-AB-65634

HACE1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65634
Additional Names:
HACE1,SPPRS
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human HACE1 (NP_065822.2).
Uniprot:
Q8IYU2
Synonyms:
E3 ubiquitin-protein ligase HACE1;HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1;HECT-type E3 ubiquitin transferase HACE1;SPPRS
Extra Details:
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor.
Shipping Conditions:
Blue Ice