E-AB-65595
MTHFD1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65595
- Additional Names:
- MTHFC,MTHFD,MTHFD1
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MTHFD1 (NP_005947.3).
- Uniprot:
- P11586
- Synonyms:
- 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic;C1-THF synthase;CIMAH;cytoplasmic C-1-tetrahydrofolate synthase;epididymis secretory sperm binding protein;methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase;MTHFC;MTHFD
- Extra Details:
- This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
- Shipping Conditions:
- Blue Ice