E-AB-65472
CGGBP1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65472
- Additional Names:
- CGGBP,CGGBP1,p20-CGGBP
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CGGBP1 (NP_003654.3).
- Uniprot:
- Q9UFW8
- Synonyms:
- 20 kDa CGG-binding protein;CGG triplet repeat-binding protein 1;CGG-binding protein 1;CGGBP;p20-CGG binding protein;p20-CGGBP;p20-CGGBP DNA-binding protein
- Extra Details:
- This gene encodes a CGG repeat-binding protein that primarily localizes to the nucleus. CGG trinucleotide repeats are implicated in many disorders as they often act as transcription- and translation-regulatory elements, can produce hairpin structures which cause DNA replication errors, and form regions prone to chromosomal breakage. CGG repeats are also targets for CpG methylation. In addition to its ability to bind CGG repeats and regulate transcription, this gene is believed to play a role in DNA damage repair and telomere protection. In vitro studies indicate this protein does not bind to methylated CpG sequences.
- Shipping Conditions:
- Blue Ice