NSUN2 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-65440
Additional Names:: MISU,MRT5,NSUN2,SAKI,TRM4
Application:: IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human NSUN2 (NP_060225.4).
Uniprot:: Q08J23
Synonyms:: 5-methycytoisine methyltransferase;MISU;mRNA cytosine C(5)-methyltransferase;MRT5;myc-induced SUN domain-containing protein;Myc-induced SUN-domain-containing protein;NOL1/NOP2/Sun domain family member 2;NOL1/NOP2/Sun domain family, member 2;NOP2/Sun domain family, member 2;NOP2/Sun RNA methyltransferase family member 2;RNA cytosine C(5)-methyltransferase NSUN2;SAKI;substrate of AIM1/Aurora kinase B;TRM4;tRNA (cytosine-5-)-methyltransferase;tRNA (cytosine-5-)-methyltransferase NSUN2;tRNA (cytosine(34)-C(5))-methyltransferase;tRNA cytosine C(5)-methyltransferase;tRNA methyltransferase 4 homolog
Extra Details:: This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.