E-AB-65363
TOP1MT Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65363
- Additional Names:
- TOP1MT
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TOP1MT (NP_443195.1).
- Uniprot:
- Q969P6
- Synonyms:
- DNA topoisomerase I, mitochondrial;mitochondrial topoisomerase IB;topoisomerase (DNA) I, mitochondrial
- Extra Details:
- This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Shipping Conditions:
- Blue Ice