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E-AB-65316

UBQLN1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65316
Additional Names:
DA41,DSK2,PLIC-1,UBQLN1,UBQN,XDRP1
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human UBQLN1 (NP_038466.2).
Uniprot:
Q9UMX0
Synonyms:
DA41;DSK2;hPLIC-1;PLIC-1;protein linking IAP with cytoskeleton 1;testicular tissue protein Li 219;ubiquilin-1;UBQN;XDRP1
Extra Details:
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice