E-AB-65294
VAV3 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65294
- Additional Names:
- VAV3
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human VAV3 (NP_006104.4).
- Uniprot:
- Q9UKW4
- Synonyms:
- guanine nucleotide exchange factor VAV3;vav 3 guanine nucleotide exchange factor;vav 3 oncogene;VAV-3
- Extra Details:
- This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Shipping Conditions:
- Blue Ice