E-AB-65293
TCIRG1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65293
- Additional Names:
- ATP6N1C,ATP6V0A3,Atp6i,OC-116kDa,OC116,OPTB1,Stv1,TCIRG1,TIRC7,Vph1,a3
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TCIRG1 (NP_006010.2).
- Uniprot:
- Q13488
- Synonyms:
- a3;Atp6i;ATP6N1C;ATP6V0A3;ATPase, H+ transporting, 116kD;OC-116kDa;OC116;OPTB1;osteoclastic proton pump 116 kDa subunit;specific 116-kDa vacuolar proton pump subunit;Stv1;T-cell immune regulator 1;T-cell immune response cDNA 7;T-cell immune response cDNA7 protein;T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a;T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3;TIRC7;V-ATPase 116 kDa subunit a3;V-ATPase 116-kDa;V-ATPase subunit a3;V-type proton ATPase 116 kDa subunit a;V-type proton ATPase 116 kDa subunit a3;vacuolar proton translocating ATPase 116 kDa subunit A;Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3;Vph1
- Extra Details:
- This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.
- Shipping Conditions:
- Blue Ice