E-AB-65278
TRIP4 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65278
- Additional Names:
- ASC-1,ASC1,HsT17391,MDCDC,SMABF1,TRIP4,ZC2HC5
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TRIP4 (NP_057297.2).
- Uniprot:
- Q15650
- Synonyms:
- activating signal cointegrator 1;ASC-1;ASC1;HsT17391;MDCDC;SMABF1;thyroid receptor-interacting protein 4;TR-interacting protein 4;TRIP-4;ZC2HC5;zinc finger, C2HC5-type
- Extra Details:
- This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).
- Shipping Conditions:
- Blue Ice