E-AB-65204
CDC23 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65204
- Additional Names:
- ANAPC8,APC8,CDC23,CUT23
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human CDC23 (NP_004652.2).
- Uniprot:
- Q9UJX2
- Synonyms:
- ANAPC8;anaphase-promoting complex subunit 8;APC8;cell division cycle 23 homolog;cell division cycle protein 23 homolog;CUT23;cyclosome subunit 8
- Extra Details:
- The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
- Shipping Conditions:
- Blue Ice