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E-AB-65136

BRMS1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65136
Additional Names:
BRMS1
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human BRMS1 (NP_056214.1).
Uniprot:
Q9HCU9
Synonyms:
breast cancer metastasis suppressor 1;breast cancer metastasis-suppressor 1
Extra Details:
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Shipping Conditions:
Blue Ice