E-AB-65105
PTPRN2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65105
- Additional Names:
- IA-2beta,IAR,ICAAR,PTPRN2,PTPRP,R-PTP-N2
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PTPRN2 (NP_570858.2).
- Uniprot:
- Q92932
- Synonyms:
- IA-2beta;IAR;IAR/receptor-like protein-tyrosine phosphatase;ICAAR;islet cell autoantigen-related protein;phogrin;protein tyrosine phosphatase receptor pi;protein tyrosine phosphatase, receptor type, N polypeptide 2;PTPRP;R-PTP-N2;receptor-type tyrosine-protein phosphatase N2;tyrosine phosphatase IA-2 beta
- Extra Details:
- This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice