E-AB-65101
PDE6D Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65101
- Additional Names:
- JBTS22,PDE6D,PDED
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PDE6D (NP_002592.1).
- Uniprot:
- O43924
- Synonyms:
- GMP-PDE delta;JBTS22;PDED;phosphodiesterase 6D, cGMP-specific, rod, delta;protein p17;retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
- Extra Details:
- This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
- Shipping Conditions:
- Blue Ice