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E-AB-65054

DRD3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65054
Additional Names:
D3DR,DRD3,ETM1,FET1
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human DRD3 (NP_000787.2).
Uniprot:
P35462
Synonyms:
D(3) dopamine receptor;D3DR;Dopamine D3 receptor;essential tremor 1;ETM1;FET1
Extra Details:
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Shipping Conditions:
Blue Ice