E-AB-65047
LZTS2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-65047
- Additional Names:
- LAPSER1,LZTS2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human LZTS2 (NP_115805.1).
- Uniprot:
- Q9BRK4
- Synonyms:
- LAPSER1;leucine zipper putative tumor suppressor 2;leucine zipper, putative tumor suppressor 2;protein LAPSER1
- Extra Details:
- The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice