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E-AB-65014

SPARC Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-65014
Additional Names:
BM-40,OI17,SPARC
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human SPARC (NP_003109.1).
Uniprot:
P09486
Synonyms:
basement-membrane protein 40;BM-40;OI17;ON;ONT;Osteonectin;Secreted protein acidic and rich in cysteine;secreted protein, acidic, cysteine-rich (osteonectin);SPARC
Extra Details:
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice