E-AB-64812
IDH3B Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64812
- Additional Names:
- IDH3B,RP46
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human IDH3B (NP_008830.2).
- Uniprot:
- O43837
- Synonyms:
- isocitrate dehydrogenase (NAD(+)) 3 beta;isocitrate dehydrogenase [NAD] subunit beta, mitochondrial;isocitrate dehydrogenase 3 (NAD(+)) beta;isocitrate dehydrogenase 3 (NAD+) beta;isocitric dehydrogenase subunit beta;NAD(+)-specific ICDH subunit beta;RP46
- Extra Details:
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Shipping Conditions:
- Blue Ice