E-AB-64803
MDFI Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64803
- Additional Names:
- I-MF,I-mfa,MDFI
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MDFI (NP_005577.1).
- Uniprot:
- Q99750
- Synonyms:
- I-MF;I-mfa;inhibitor of MyoD family a;myoD family inhibitor;myogenic repressor I-mf
- Extra Details:
- This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
- Shipping Conditions:
- Blue Ice