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E-AB-64684

LIG3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-64684
Additional Names:
LIG2,LIG3
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human LIG3 (NP_039269.2).
Uniprot:
P49916
Synonyms:
DNA ligase 3;DNA ligase III;LIG2;LIG3alpha;ligase II, DNA, ATP-dependent;ligase III, DNA, ATP-dependent;polydeoxyribonucleotide synthase [ATP] 3
Extra Details:
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Shipping Conditions:
Blue Ice