E-AB-64616
TARDBP Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64616
- Additional Names:
- ALS10,TARDBP,TDP-43,TDP43
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TARDBP (NP_031401.1).
- Uniprot:
- Q13148
- Synonyms:
- ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43
- Extra Details:
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
- Shipping Conditions:
- Blue Ice