E-AB-64562
PCNA Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64562
- Additional Names:
- ATLD2,PCNA
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PCNA (NP_002583.1).
- Uniprot:
- P12004
- Synonyms:
- ATLD2;cyclin;DNA polymerase delta auxiliary protein;proliferating cell nuclear antigen
- Extra Details:
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
- Shipping Conditions:
- Blue Ice