E-AB-64490
SCYL2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64490
- Additional Names:
- CVAK104,SCYL2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human SCYL2 (NP_060458.3).
- Uniprot:
- Q6P3W7
- Synonyms:
- AMC4;AMCNACC;coated vesicle-associated kinase of 104 kDa;CVAK104;SCY1-like 2;SCY1-like protein 2;SCY1-like, kinase-like 2
- Extra Details:
- The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.
- Shipping Conditions:
- Blue Ice