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E-AB-64412

AKR1C1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-64412
Additional Names:
2-ALPHA-HSD,20-ALPHA-HSD,AKR1C1,C9,DD1,DD1/DD2,DDH,DDH1,H-37,HAKRC,HBAB,MBAB
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human AKR1C1 (NP_001344.2).
Uniprot:
Q04828
Synonyms:
2-ALPHA-HSD;20 alpha-hydroxysteroid dehydrogenase;20-ALPHA-HSD;20-alpha-hydroxysteroid dehydrogenase;aldo-keto reductase C;aldo-keto reductase family 1 member C1;C9;chlordecone reductase homolog HAKRC;DD1;DD1/DD2;DDH;DDH1;dihydrodiol dehydrogenase 1;dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase;dihydrodiol dehydrogenase 1/2;H-37;HAKRC;HBAB;hepatic dihydrodiol dehydrogenase;high-affinity hepatic bile acid-binding protein;indanol dehydrogenase;MBAB;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;type II 3-alpha-hydroxysteroid dehydrogenase
Extra Details:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Shipping Conditions:
Blue Ice