E-AB-64392
HSD17B8 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64392
- Additional Names:
- D6S2245E,FABG,FABGL,H2-KE6,HKE6,HSD17B8,KE6,RING2,SDR30C1,dJ1033B10.9
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human HSD17B8 (NP_055049.1).
- Uniprot:
- Q92506
- Synonyms:
- (3R)-3-hydroxyacyl-CoA dehydrogenase;17-beta-HSD 8;17-beta-hydroxysteroid dehydrogenase 8;3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit;3-oxoacyl-[acyl-carrier-protein] reductase;D6S2245E;dJ1033B10.9;estradiol 17-beta-dehydrogenase 8;estrogen 17-oxidoreductase;FABG;FABGL;H2-KE6;HKE6;KAR alpha subunit;ke-6;KE6;protein Ke6;really interesting new gene 2 protein;RING2;SDR30C1;short chain dehydrogenase/reductase family 30C member 1;testosterone 17-beta-dehydrogenase 8
- Extra Details:
- In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
- Shipping Conditions:
- Blue Ice