E-AB-64383
(KO Validated) MTCH2 Polyclonal Antibody
Size
£210.60
Was £234.00
- SKU:
- E-AB-64383
- Additional Names:
- HSPC032,MIMP,MTCH2,SLC25A50
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MTCH2 (NP_055157.1).
- Uniprot:
- Q9Y6C9
- Synonyms:
- 2310034D24Rik;HSPC032;met-induced mitochondrial protein;MIMP;mitochondrial carrier homolog 2;SLC25A50;solute carrier family 25, member 50
- Extra Details:
- This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
- Shipping Conditions:
- Blue Ice