E-AB-64364
RUFY3 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64364
- Additional Names:
- RIPX,RUFY3,SINGAR1,ZFYVE30
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human RUFY3 (NP_055776.1).
- Uniprot:
- Q7L099
- Synonyms:
- protein RUFY3;rap2 interacting protein x;Rap2-interacting protein x;RIPX;RUN and FYVE domain-containing protein 3;SINGAR1;single axon-regulated protein;single axon-related 1;ZFYVE30
- Extra Details:
- This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice