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E-AB-64359

ATP23 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-64359
Additional Names:
ATP23,KUB3,XRCC6BP1
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ATP23 (NP_150592.1).
Uniprot:
Q9Y6H3
Synonyms:
Ku70-binding protein 3;KUB3;mitochondrial inner membrane protease ATP23 homolog;XRCC6-binding protein 1;XRCC6BP1
Extra Details:
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice