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E-AB-64355

TLX1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-64355
Additional Names:
HOX11,TCL3,TLX1
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TLX1 (NP_001182446.1).
Uniprot:
P31314
Synonyms:
homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch);homeobox protein Hox-11;HOX11;proto-oncogene TCL-3;T-cell leukemia homeobox protein 1;T-cell leukemia/lymphoma protein 3;TCL3
Extra Details:
This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice