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E-AB-64205

SHMT1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-64205
Additional Names:
CSHMT,SHMT,SHMT1
Application:
IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human SHMT1 (NP_683718.1).
Uniprot:
P34896
Synonyms:
CSHMT;cytoplasmic serine hydroxymethyltransferase;glycine hydroxymethyltransferase;serine hydroxymethyltransferase 1 (soluble);serine hydroxymethyltransferase, cytosolic;serine methylase;SHMT
Extra Details:
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice