E-AB-64060
DVL1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64060
- Additional Names:
- DRS2,DVL,DVL1,DVL1L1,DVL1P1
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human DVL1 (NP_004412.2).
- Uniprot:
- O14640
- Synonyms:
- dishevelled 1 (homologous to Drosophila dsh);dishevelled-1;dishevelled, dsh homolog 1;DRS2;DSH homolog 1;DVL;DVL1L1;DVL1P1;segment polarity protein dishevelled homolog DVL-1
- Extra Details:
- DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
- Shipping Conditions:
- Blue Ice