E-AB-64038
CDK9 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-64038
- Additional Names:
- C-2k,CDC2L4,CDK9,CTK1,PITALRE,TAK
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CDK9 (NP_001252.1).
- Uniprot:
- P50750
- Synonyms:
- C-2k;CDC2-related kinase;CDC2L4;cell division cycle 2-like protein kinase 4;cell division protein kinase 9;CTK1;cyclin-dependent kinase 9;PITALRE;serine/threonine protein kinase PITALRE;Serine/threonine-protein kinase PITALRE;TAK;tat-associated kinase complex catalytic subunit
- Extra Details:
- The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
- Shipping Conditions:
- Blue Ice