E-AB-63997
HDAC4 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63997
- Additional Names:
- AHO3,BDMR,HA6116,HD4,HDAC-4,HDAC-A,HDAC4,HDACA
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human HDAC4 (NP_006028.2).
- Uniprot:
- P56524
- Synonyms:
- AHO3;BDMR;HA6116;HD4;HDAC-4;HDAC-A;HDACA;histone deacetylase 4;histone deacetylase A
- Extra Details:
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
- Shipping Conditions:
- Blue Ice