SPTAN1 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-63995
Additional Names:: EIEE5,NEAS,SPTA2,SPTAN1
Application:: IHC, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SPTAN1 (NP_001123910.1).
Uniprot:: Q13813
Synonyms:: alpha-fodrin;alpha-II spectrin;DEE5;EIEE5;epididymis secretory sperm binding protein;fodrin alpha chain;NEAS;spectrin alpha chain, non-erythrocytic 1;spectrin, non-erythroid alpha chain;spectrin, non-erythroid alpha subunit;SPTA2
Extra Details:: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.