E-AB-63882
ABCB11 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63882
- Additional Names:
- ABC16,ABCB11,BRIC2,BSEP,PFIC-2,PFIC2,PGY4,SPGP
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ABCB11 (NP_003733.2).
- Uniprot:
- O95342
- Synonyms:
- ABC member 16, MDR/TAP subfamily;ABC16;ATP-binding cassette sub-family B member 11;ATP-binding cassette, sub-family B (MDR/TAP), member 11;bile salt export pump;BRIC2;BSEP;PFIC-2;PFIC2;PGY4;progressive familial intrahepatic cholestasis 2;sister p-glycoprotein;SPGP
- Extra Details:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
- Shipping Conditions:
- Blue Ice