VTI1A Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-63813
Additional Names:: MMDS3,MVti1,VTI1A,VTI1RP2,Vti1-rp2
Application:: WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human VTI1A (NP_660207.2).
Uniprot:: Q96AJ9
Synonyms:: MMDS3;MVti1;SNARE Vti1a-beta protein;vesicle transport through interaction with t-SNAREs homolog 1A;vesicle transport v-SNARE protein Vti1-like 2;Vti1-rp2;VTI1RP2
Extra Details:: The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.