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E-AB-63791

ADRM1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-63791
Additional Names:
ADRM1,ARM-1,ARM1,GP110
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ADRM1 (NP_008933.2).
Uniprot:
Q16186
Synonyms:
110 kDa cell membrane glycoprotein;adhesion regulating molecule 1;Adhesion-regulating molecule 1;ARM-1;ARM1;GP110;M(r) 110,000 surface antigen;proteasomal ubiquitin receptor ADRM1;proteasome regulatory particle non-ATPase 13;proteasome ubiquitin receptor;PSMD16;rpn13 homolog
Extra Details:
This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice